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- Validation of the specific role of gene knockouts in lipid metabolism
The regulation of different metabolic pathways in health and disease is essential for innovative diagnostics and therapeutical approaches. Knowing the specific role of each gene, protein, or enzyme...
- How mRNA therapeutics are delivered into cells
Researchers have found where and how mRNA arrives in a cell to modify or deliver genetic information, a crucial process for the development of novel therapies. In recent years, ribonucleic acid ...
- New chemical tools can control the concentration of lipids in living cells
Lipids, or fats, have many functions in our body: They form membrane barriers, store energy or act as messengers, which regulate cell growth and hormone release. Many of them are also biomarkers fo...
- Neural networks let microscopists see more
Modern microscopes can record many hours of 3D time-lapse movies of every cell as an organism develops. Just as for regular photography, fluorescence microscopy requires enough light to avoid dark ... - A new non-invasive way to study cells and embryonic development
Simple motion inside biological cells, such as the streaming of cytoplasm - the liquid cell interior - is widely believed to be essential for cells and the development of complex organisms. But due...
- Live imaging of large living organisms
Light-sheet microscopy is one of the most powerful methods for imaging the development and function of whole living organisms. However, achieving high-resolution images with these microscopes requi...