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- Large molecules transported into living cells
It is one of the big pharmacological questions: How do you get large functional biomolecules like proteins or antibodies into a living cell? Linking antibodies or proteins with cell-penetrating pep...
- Determining the atomic structure of natural products more rapidly and accurately
Many drugs are derived from natural products. But before natural products can be exploited, chemists must first determine their structure and stereochemistry. This can be a major challenge, particu...
- Novel contrast medium promises deep insights into cell processes
Imagine tracing the fate of specific cells in deep layers of tissue using minute amounts of an externally triggered contrast medium. The almost unimaginable is within reach today! A new contrast me... - Identification of a key molecule for the neurotransmitter release in synapses
The contact areas between nerve cells are called synapses. What happens there lies at the heart of communication between nerve cells. Communication starts with the release of chemical messengers kn... - Introducing nano antibodies into living cells
Scientists at the Technische Universität Darmstadt, Ludwig Maximilians University (LMU) Munich and the Leibniz Institute for Molecular Pharmacology (FMP) have managed to introduce tiny antibodies i... - Viruses over antibiotics: Determining the 3D structure of phages
Phages have become a focus of research in the battle against antibiotic resistance. These bacteria-eating viruses have already proven effective in experiments against multidrug-resistant bacteria. ... - Explaining memory on the molecular level?
The molecular pharmacologist and biochemist Volker Haucke has been granted funding in the Koselleck programme of the DFG for highly innovative research into the mechanisms of neuronal communication...
- Atomic structures of proteins elucidated
The more we know about the agents that cause disease, the more specifically we will be able to combat them. These are the words of Prof. Adam Lange of the Leibniz-Institut für Molekulare Pharmakolo...
- Down to the atom: Bacterial skeleton in close-up by solid-state NMR
For a long time, bacteria were considered to be primitive structures, and it was not until the most modern of imaging techniques were used that their fine inner structure was discovered. The Berlin... - Rapid and efficient technique for targeted chemoenzymatic functionalization of proteins
Selective intermolecular recognition is at the heart of all biological processes. Thus proteins that bind specifically to complementary chemical structures are also indispensable for many biochemic...
- First 3D Model of a Synapse
A glance into a new world for neuroscience: research team from Göttingen led by Prof. Dr. Silvio O. Rizzoli present the first scientifically accurate 3D model of a synapse. This effort has been mad...