Triple Quad LC-MS for detection of luciferin-6'-p-nitrobenzyl ether - a footprint of peroxynitrite
Radoslaw Podsiadly, Aleksandra Grzelakowska, Lodz University of Technology - Institute of Polymer and Dye Technology
Jacek Zielonka, Medical College of Wisconsin
Peroxynitrite (ONOO^-), a highly reactive oxidizing and nitrating agent is generated via a spontaneous, diffusion-controlled reaction between nitric oxide (·NO) and superoxide radical anion (O^2·-). Peroxynitrite has been implicated as a key pathophysiological intermediate in various diseases, incl...