Senior Scientist Computational Chemistry (m/f/d)

You will design the drugs that will address high unmet medical needs, in oncology & immuno-oncology. You will impact, and potentially lead, multi-disciplinary project teams, including highly skilled medicinal chemists, by efficiently and pro-actively applying all computer-aided drug design methods that can help finding the perfect drug: structure- and ligand-based design, virtual screening, Free-Energy-Perturbation calculations, emerging Artificial Intelligence applications, and advanced data analysis techniques.

  • PhD in chemistry, physics, bioinformatics or related discipline and more than 3 years of professional experience in an industry setting
  • Skilled at forming and articulating clear scientific hypotheses and at leading creative and interactive dialogues with medicinal chemists
  • Extensive knowledge in 3D molecular design including protein-ligand interactions and small molecule conformations, homology modeling, and are proficient in chemoinformatics
  • Good knowledge of organic synthesis or, even better, medicinal chemistry
  • Strong background in IT
  • Proficient using state-of-the-art modeling software (e.g. MOE, Schrödinger suite, CCDC...)
  • Experienced in mining data to extract knowledge and building predictive models
  • Familiar in automating workflows using scripting languages and/or pipelining tools
  • Excellent communication skills in English; German is a bonus

» Job description

Merck KGaA
64293 Darmstadt