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Juno Therapeutics GmbH

Associate Engineer - FPLC Expert (m/f)



Juno Therapeutics, a Celgene Company, is developing novel cellular immunotherapies based on two distinct and complementary platforms - Chimeric Antigen Receptors (CARs) and T Cell Receptors (TCRs) technologies. Our goal is to revolutionize medicine by re-engaging the body's immune system to treat cancer. For our Process Engineering Team located in Munich, we are looking for an

Associate Engineer - FPLC Expert (m/f)


as temporary maternity leave replacement from 1st Dec. 2018 till 31st March 2020.

Primary responsibilities:

  • FPLC purification of proteins
  • Planning and execution of (protein purification) process development, optimization and scale-up, with focus on FPLC
  • Development of GMP-conform production processes and facilitate the transfer from Technical Development at lab scale to GMP manufacturing
  • Support manufacturing during process and equipment implementation, as well as technical and practical troubleshooting
  • Communication with external suppliers
  • Authoring of process relevant documentation for GMP production (Forms, Master Batch Records, SOPs)
  • Support of our production team in performing cGMP manufacturing activities according to standard operating procedures (SOPs) and batch records in accordance with assigned daily tasks and production schedule
  • Experience with Quality Systems (Deviations, CAPAs, Change Control, etc.) would be beneficial, but not mandatory
  • Identification, implementation, and qualification of new devices. Validation assistance in our production facility
  • Expertise in documentation and presentation of results, compilation of development reports
  • Training of (new) staff on processes and process relevant devices

Required qualifications:

  • Working knowledge and profound practical experience with AKTA systems and UNICORN software is required
  • Extensive experience with FPLC processes (column packing and chromatography (HIC, IEX, Affinity, CIP procedures)
  • Knowledge of protein purification demonstrated through purification of several types of proteins using a wide range of methods and affinity tags
  • 1-2 years of experience relevant to protein purification/process development is preferred
  • The successful candidate will have experience working in multi-disciplinary teams
  • Networking and communication skills
  • Attention to detail and the ability to follow standard operating procedures and deliver accurate documentation are essential
  • Dedicated team player
  • Ability to work in a fast developing environment, according to set priorities and timelines
  • Enthusiasm, self-motivation, flexibility, and readiness/ability to learn new methods are critical

Educational requirements:

  • MTA / BTA / CTA (Technician) with at least 5 years of relevant experience
  • BS or MS in Biological Sciences / Biological Engineering with at least 2 years of relevant experience (for BS) or at least 1 year of relevant experience (for MS)

Juno Therapeutics is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, age, sex, sexual orientation, gender identity or gender expression, national origin, citizenship, disability, genetic information, veteran status or military status, or any other classification protected by applicable law. Juno complies with all applicable national, state/provincial, and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements. All applicants must have authorization to work for Juno Therapeutics in the country in which the position is based.

Juno reports payments and other transfers of value to health care providers, as required by federal and state transparency laws and implementing regulations. These laws and regulations require Juno to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs expenses while interviewing with Juno that we pay or reimburse, your name, address and the amount of payments made will be reported to the government.


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Einsatzort:
81675 München
Arbeitsbeginn:
01.12.2018
Befristet:
Ja, bis 31.03.2020
Kontaktdaten:
Juno Therapeutics GmbH
Grillparzerstraße 10
D-81675 München

Tel.: +49 (0)89 / 380 357-70
Web: www.junotherapeutics.com